Biotech researcher examining cell culture sample in Cellicure laboratory

CAR-NK Technologies

CAR-NK therapy builds upon allogeneic NK Cells (“Natural Killer”) providing the NK cells with the information necessary to recognize, target, and destroy cancer cells. CAR-NK technology is proving to be a superior alternative to CAR-T, with many advantages such as multifunctionality, low toxicity, and universal patient applications, i.e., not patient-specific.

Our technology platform

Cellicure’s Solution

Based on NK biology and NK receptor signaling properties, Cellicure has developed the “Complete Signaling CAR (csCAR)” solution. This innovative technology overcomes the challenges of the receptor cell barrier by deploying the patented and innovative signal 3 and 4 elements as well as our own hinge and transmembrane domain. 

Schematic of Cellicure csCAR structure showing proprietary signaling domains for enhanced NK cell activation.

OUR TECHNOLOGIES

Cellicure’s Solutions

Cellicure's proprietary systems deliver high-yield NK cell treatments engineered to maximize efficacy while minimizing toxicity across multiple cancer types and inflammatory conditions.

Effic-NK™ expansion

Feeder-free system producing clinical-grade NK cells with enhanced expansion and reduced manufacturing complexity.

Saftein™ technology

Proprietary safety mechanism designed to improve NK cell survival and function while eliminating cytokine-related toxicity.

Solid tumor targeting

Engineered immunotherapies specifically developed to penetrate and destroy solid tumor microenvironments effectively.

Hematological cancer focus

Tailored NK cell treatments addressing blood cancers with precision activation and selective tumor cell recognition.